Supplementary MaterialsSI. 6.6 Hz, 2H), 2.24 (s, 3H). 13C NMR (CDCl3, 75 MHz): 159.1, 136.3, 131.9, 131.1, 129.7, 128.4, 128.2, 123.4, 117.7, 113.6, 88.3, 85.3, 59.3, 57.8, 55.4, 37.8 ppm. IR (thin film): 2948, 2834, 2786, 1642, 1609, 1583, 1507, 1488, 1441, 1301, Calcipotriol cell signaling 1244, 1169, 1126, 1107, 1033, 994, 962, 916, 850, 807, 778, 754, 689, 583, 524 cm?1. HRMS (ESI-TOF) = 0.75 (6:4 hexanes/EtOAc). 1H NMR (CDCl3, 500 MHz): 7.65C7.61 (m, 2H), 7.59C7.56 (m, 2H), 7.40C7.34 (m, 5H), 5.90C5.91 (m, 1H), 5.35 (dd, = 17.0 Hz, 2.0 Hz, 1H), 5.23 (dd, = 10.5 Hz, 2.0 Hz, 1H), 4.98 (s, 1H), 3.21 (d, = 6.0 Hz, 2H), 2.26 (s, 3H). 13C NMR (CDCl3, 125 MHz): 137.5, 135.9, 133.3, 131.8, 129.8, 128.4, 128.3 (2), 122.9, 117.9, 88.7, 84.2, 59.1, 57.8, 37.6 ppm. IR (thin film): 1487, 1442, 1402, 1089, 1014, Calcipotriol cell signaling 994, 962, 920, 853, 796, 689, 592, 582 cm?1. HRMS (ESI-TOF) = 0.68 (6:4 hexanes/EtOAc). 1H NMR (CDCl3, 500 MHz): 7.43 (d, = 8.5 Hz, 2H), 6.86 (d, = 8.5 Hz, 2H), Calcipotriol cell signaling 5.84C5.81 (m, 1H), 5.23 (dd, = 17.0 Hz, 1.5 Hz, 1H), 5.12 (d, = 6.5 Hz, 1H), 4.62 (s, 1H), 3.04 (t, = 7.5 Hz, 2H), 2.10 (s, 3H), 1.40C1.32 (m, 1H), 0.84C0.80 (m, Calcipotriol cell signaling 2H), 0.75C0.71 (m, 2H) ppm. 13C NMR (CDCl3, 125 MHz): 159.1, 136.6, 131.7, 129.7, 117.5, 113.5, 91.7, 77.5, 59.0, 57.7, 55.5, 37.8, 8.8, 0.2 ppm. IR (slim film): 1610, 1507, 1361, 1243, 1109, 1035, 1016, 999, 918, 982, 850, 808, 777, 584 cm?1. HRMS (ESI-TOF) [M + H]+ = 0.75 (6:4 hexanes/EtOAc). 1H NMR (CDCl3, 500 MHz): 7.59 (d, = 8.5 Hz, 2H), 7.55C7.54 (m, 2H), 7.53C7.51 (m, 3H), 6.89 (d, = 8.5 Hz, 2H), 5.90C5.83 (m, 1H), 5.27 (d, = 17.0 Hz, 1H), 5.14 (d, = 10.0 Hz, 1H), 5.05 (s, 1H), 3.82 (s, 3H), 3.28 (dd, = 14.0 Hz, 2.0 Hz, 2H), 3.04 (dd, = 14.0 Hz, 8.0 Hz, 2H) ppm. 13C NMR (CDCl3, 125 MHz): 159.1, 136.8, 132.1, 132.0, 131.6, 129.6, 128.5, 128.3, 123.6, 117.5, 113.7, 88.9, 85.9, 56.2, 55.5, 53.7 ppm. IR (thin film): 1609, 1508, 1489, 1447, 1301, 1246, 1170, 1108, 1036, 995, 971, 919, 848, 811, 759, 691 cm?1. HRMS (ESI-TOF) [M + H]+ = 0.74 (6:4 hexanes/EtOAc). 1H NMR (CDCl3, 500 MHz): 7.47C7.44 (m, 2H), 7.32C7.29, (m, 3H), 5.88 (ddt, = 6.0 Hz, 10.5 Hz, 17.0 Hz, 1H), 5.27 (d, = 17.0 Hz, 2H), 5.17 (d, = 10.5 Hz, 2H), 3.23 (dd, = 5.0 Hz, 13.5 Hz, Calcipotriol cell signaling 1H), 3.19 (d, = 9.0 Hz, 1H), 2.91 (dq, = 16.5 Hz, 6.5 Hz, 1H), 1.13 (d, = 6.5 Hz, 3H), 1.05 (d, = 6.5 Hz, 3H) ppm. 13C NMR (CDCl3, 125 MHz): 136.2, 131.7, 128.4, 128.2, 127.8, 123.6, 117.4, 86.4, 63.2, 58.2, 37.8, 31.0, 20.8, 19.9 ppm. IR (slim film): 1952, 1643, 1598, 1488, 1443, 1412, 1383, 1364, 1326, 1261, 1208, 1163, 1096, 1069, 1027, 995, 917, 753, 689, 595, 545 cm?1. HRMS (ESI-TOF) [M + H]+ = 0.44 (6:4 hexanes/EtOAc). 1H NMR (CDCl3, 500 MHz): 7.33 (d, = 8.3 Hz, 2H), 7.09 (d, = 8.3 Hz, 2H), 5.89 (ddt, = 4.0 Hz, 6.5 Hz, 10.3 Hz, 1H), 5.25 (d, = 17.5 Hz, 1H), 5.17 (d, = 10.3 Hz, 1H), 3.54 (s, 1H), 3.14 (d, = 6.5 Hz, 2H), 2.38 (s, 3H), 2.33 (s, 3H) ppm. 13C NMR (CDCl3, 125 MHz): 138.1, 135.1, 131.6, 129.0, 120.1, 118.3, 85.6, 83.3, 59.1, 46.0, 41.6, 21.4 ppm. IR (thin film): 2918, 1787, 1643, 1509, 1449, 1359, 1325, 1254, 1193, 1128, 1107, 1032, 994, 968, 921, 814, 677, 629, 566 cm?1. HRMS (ESI-TOF) [M + H]+ = 0.22 (2:1 hexanes/EtOAc). 1H NMR (CDCl3, 300 MHz): 7.54C7.48 (m, 4H), 7.33C7.31 (m, 3H), 6.9 (d, = 8.7 Hz, 2H), 5.18 (s, 1H), 3.81 (s, 3H), 2.56 (s, 3H), 1.81 (s, 1H) ppm. 13C NMR (CDCl3, 75 MHz): 159.2, 132.4, 131.7, 128.8, 128.3, 128.1, 123.1, 113.8, 89.2, 85.5, 55.6, 55.3, 33.7 ppm. IR (thin film): 2953, 2834, CD244 2790, 1609, 1584, 1508, 1488, 1462,.
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a 67 kDa type I transmembrane glycoprotein present on myeloid progenitors
and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes
Apoptosis
bladder
brain
breast
cell cycle progression
cervix
CSP-B
Cyproterone acetate
EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck
EM9
endometrium
erythrocytes
F3
Goat polyclonal to IgG H+L)
Goat polyclonal to IgG H+L)Biotin)
GRK4
GSK1904529A
Igf1
Mapkap1
monocytes andgranulocytes. CD33 is absent on lymphocytes
Mouse monoclonal to CD33.CT65 reacts with CD33 andtigen
Palomid 529
platelets
PTK) or serine/threonine
Rabbit Polyclonal to ARNT.
Rabbit polyclonal to BMPR2
Rabbit Polyclonal to CCBP2.
Rabbit Polyclonal to EDG4
Rabbit polyclonal to EIF4E.
Rabbit polyclonal to IL11RA
Rabbit polyclonal to LRRIQ3
Rabbit Polyclonal to MCM3 phospho-Thr722)
Rabbit Polyclonal to RBM34
SB 216763
SKI-606
SNX-5422
STK) kinase catalytic domains. Epidermal Growth factor receptor
stomach
stomach and in squamous cell carcinoma.
TNFSF8
TSHR
VEGFA
vulva