Background To investigate the reproducibility of macular ganglion cell-inner plexiform layer (GCIPL) thickness measurement in normal eyes determined by different operators and two different raster scanning protocols of Cirrus high-definition optical coherence tomography (HD-OCT). ICCs of Macular Cube 512??128 and 200??200 protocol were 0.953 to 0.987 and 0.953 to 0.991, respectively; and the inter-protocol ICCs Epirubicin Hydrochloride novel inhibtior were 0.876 to 0.991. All CoVs were 1.5%. Conclusions Cirrus HD-OCT can measure macular GCIPL thickness in normal eyes with excellent reproducibility. The measurements determined by Macular Cube 512??128 and 200??200 protocol were highly consistent and both protocols were eligible for macular GCIPL thickness measurement. value 0.05 was considered statistically significant. Results A total of 108 participants were enrolled in the study based on the inclusion criteria. Of these, 6 participants were excluded because of segmentation failure of the OCT images. Thus, the analyses within this research had been predicated on data from 102 topics (52 men and 50 females). The topics ranged in age group from 19 to 75?years (mean, 46.0??16.2?years). The IOP ranged from 9 to 19?mmHg (14.3??2.5?mmHg). The spherical exact carbon copy of refractive mistake ranged from ?5.25 to +2.00 D (?0.57??1.88 D). The mean Epirubicin Hydrochloride novel inhibtior deviation from the visible field tests ranged from ?2.05 to at least one 1.74?dB (?0.77??0.84?dB). Mean beliefs of the common, minimum, excellent, superonasal, inferonasal, second-rate, inferotemporal, and superotemporal macular GCIPL width measured by both operators had been displayed in Desk ?Desk1.1. There is no factor from the three repeated measurements from the GCIPL width variables by each operator, as well as the difference from the GCIPL width measured Epirubicin Hydrochloride novel inhibtior by both operators also demonstrated no statistical significance (all worth 0.05). Desk ?Desk22 showed the intra- and inter- operator ICC for GCIPL width measurements, which the cheapest and highest information were the common GCIPL width and least GCIPL width, respectively. Desk 1 Goat polyclonal to IgG (H+L) GCIPL thickness (Mean??SD, m) measured by two operators using macular cube 512??128 scanning protocol intraclass correlation coefficient, confidence interval, coefficients of variation Mean values of the average, minimum and sectorial GCIPL thickness determined by Macular Cube 512??128 and Macular Cube 200??200 scanning protocols were displayed in Table ?Table3.3. There was no significant difference of the three repeated measurements of the GCIPL thickness determined by each protocol, and the differences of the GCIPL thickness determined by the two protocols also showed no statistical significance (all value 0.05). However, the average signal strength of Macular Cube 512??128 and Macular Cube 200??200 scanning protocols was 8.54??1.13 and 7.60??1.06, respectively. The difference between each protocol was statistically significant (intraclass correlation coefficient, confidence interval, coefficients of variation Table 5 The correlation of mean signal strength and coefficient of variation (CoV) of repeated measurements of GCIPL thickness obtained by two macular cube scanning protocols thead th rowspan=”1″ colspan=”1″ /th th colspan=”2″ rowspan=”1″ Macula Cube 512??128 Protocol /th th colspan=”2″ rowspan=”1″ Macula Cube 200??200 Protocol /th th rowspan=”1″ colspan=”1″ Parameter /th th rowspan=”1″ colspan=”1″ em r /em a /th th rowspan=”1″ colspan=”1″ em P /em /th th rowspan=”1″ colspan=”1″ em r /em a /th th rowspan=”1″ colspan=”1″ em P /em /th /thead Common?0.2610.008?0.2100.034Minimum?0.2430.014?0.372 0.001Superotemporal?0.1790.072?0.2080.036Superior?0.0640.5250.0290.774Superonasal?0.1350.176?0.0430.669Inferonasal?0.2800.004?0.1860.062Inferior0.0250.805?0.2930.003Inferotemporal?0.0490.627?0.2880.003 Open in a individual window aPearsons correlation coefficient Discussion In this study, we evaluated the intra- and inter-operator reproducibility of macular GCIPL thickness measurement and investigated the reproducibility of the two available raster scanning protocols of the Cirrus HD-OCT in a Chinese population. Generally, we confirmed that this Cirrus HD-OCT could measure macular GCIPL thickness Epirubicin Hydrochloride novel inhibtior in normal eyes with excellent reproducibility. In our study, all ICCs of the macular GCIPL thicknesses ranged between 0.875 and 0.992, and the CoVs were 1.5%. The ICCs were highest for the common GCIPL and most affordable for the minimal GCIPL thickness. These results had been based on the previous results. Choi et al. seen the reproducibility of macular GCIPL thicknesses in 44 glaucoma sufferers. The ICCs had been between 0.96 and 0.99, as well as the CoVs were 3% [5]. In 50 glaucoma sufferers, Mwanza et al. discovered that all intervisit ICCs ranged between 0.94 and 0.98 as well as the CoVs were 5% [6]. Our outcomes.
Tag Archives: Epirubicin Hydrochloride novel inhibtior
Categories
- 34
- 5- Receptors
- A2A Receptors
- ACE
- Acetylcholinesterase
- Adenosine Deaminase
- Adenylyl Cyclase
- Adrenergic ??2 Receptors
- Alpha2 Adrenergic Receptors
- Annexin
- Antibiotics
- ATPase
- AXOR12 Receptor
- Ca2+ Ionophore
- Cannabinoid
- Cannabinoid (GPR55) Receptors
- CB2 Receptors
- CCK Receptors
- Cell Metabolism
- Cell Signaling
- Cholecystokinin2 Receptors
- CK1
- Corticotropin-Releasing Factor1 Receptors
- DHCR
- DMTases
- DNA Ligases
- DNA Methyltransferases
- Dopamine D1 Receptors
- Dopamine D3 Receptors
- Dopamine D4 Receptors
- Endothelin Receptors
- EP1-4 Receptors
- Epigenetics
- Exocytosis & Endocytosis
- Fatty Acid Synthase
- Flt Receptors
- GABAB Receptors
- GIP Receptor
- Glutamate (Kainate) Receptors
- Glutamate (Metabotropic) Group III Receptors
- Glutamate (NMDA) Receptors
- Glutamate Carboxypeptidase II
- Glycogen Phosphorylase
- Glycosyltransferase
- GnRH Receptors
- Heat Shock Protein 90
- hERG Channels
- Hormone-sensitive Lipase
- IKK
- Imidazoline Receptors
- IMPase
- Inositol Phosphatases
- Kisspeptin Receptor
- LTA4 Hydrolase
- M1 Receptors
- Matrixins
- Melastatin Receptors
- mGlu Group III Receptors
- mGlu5 Receptors
- Monoamine Oxidase
- Motilin Receptor
- My Blog
- Neutrophil Elastase
- Nicotinic (??4??2) Receptors
- NKCC Cotransporter
- NMU Receptors
- Nociceptin Receptors
- Non-Selective
- Non-selective 5-HT
- OP3 Receptors
- Opioid, ??-
- Orexin2 Receptors
- Other
- Other Oxygenases/Oxidases
- Other Transcription Factors
- p38 MAPK
- p53
- p56lck
- PAF Receptors
- PDPK1
- PKC
- PLA
- PPAR
- PPAR??
- Proteasome
- PTH Receptors
- Ras
- RNA Polymerase
- Serotonin (5-HT2B) Receptors
- Serotonin Transporters
- Sigma2 Receptors
- Sodium Channels
- Steroid Hormone Receptors
- Tachykinin NK1 Receptors
- Tachykinin NK2 Receptors
- Tachykinin, Non-Selective
- Telomerase
- Thyrotropin-Releasing Hormone Receptors
- Topoisomerase
- trpp
- Uncategorized
- USP
Recent Posts
- 2012) using the Phenotypic Characteristic Search for human strains with markers for resistance to Adamantane, Oseltamivir, or both drugs
- Tissue were homogenized into single-cell suspensions and put through red bloodstream cell lysis
- A phase I/II study investigated the safety and efficacy of concurrent local palliative RT and durvalumab (PD-L1 inhibitor) in 10 patients with unresectable or metastatic advanced solid tumors [136]
- We believe that this hypothesis-generating study could open new avenues for exploring oxidative stress as a potential pathogenetic and, hypothetically, therapeutic target for mitigating CLL strong class=”kwd-title” Keywords: Leukemia, Lymphocytic, Gilbert’s, Syndrome Gilbert’s syndrome (GS) is the most common inherited disorder of bilirubin glucuronidation
- Such costs aren’t simple for tertiary-care hospitals in growing countries sometimes, since these already are powered by minimal budget which switches into provision of fundamental medical services mostly, laboratory, radiology, pharmacy services, and bed space
Tags
a 67 kDa type I transmembrane glycoprotein present on myeloid progenitors
and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes
Apoptosis
bladder
brain
breast
cell cycle progression
cervix
CSP-B
Cyproterone acetate
EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck
EM9
endometrium
erythrocytes
F3
Goat polyclonal to IgG H+L)
Goat polyclonal to IgG H+L)Biotin)
GRK4
GSK1904529A
Igf1
Mapkap1
monocytes andgranulocytes. CD33 is absent on lymphocytes
Mouse monoclonal to CD33.CT65 reacts with CD33 andtigen
Palomid 529
platelets
PTK) or serine/threonine
Rabbit Polyclonal to ARNT.
Rabbit polyclonal to BMPR2
Rabbit Polyclonal to CCBP2.
Rabbit Polyclonal to EDG4
Rabbit polyclonal to EIF4E.
Rabbit polyclonal to IL11RA
Rabbit polyclonal to LRRIQ3
Rabbit Polyclonal to MCM3 phospho-Thr722)
Rabbit Polyclonal to RBM34
SB 216763
SKI-606
SNX-5422
STK) kinase catalytic domains. Epidermal Growth factor receptor
stomach
stomach and in squamous cell carcinoma.
TNFSF8
TSHR
VEGFA
vulva