We investigated interactions between HIV and aging about brain function demands

We investigated interactions between HIV and aging about brain function demands using functional magnetic resonance imaging (fMRI). Health (A.M., S.L., and R.E.) and MH22005, AI47033 (F.V.). Footnotes The authors do not have a commercial or additional association that might pose a conflict of interest (e.g., pharmaceutical stock ownership, consultancy, advisory table membership, relevant patents, or research funding). This data was offered at the Conference on Retrovirus and Opportunistic Infections (CROI), February 2009, Montreal, Canada, Abstract # 157. Conflict of interest Beau M. Ances- no conflict of interest Florin Vaida C no conflict of interest Melinda J. Yeh- no conflict of interest Christine L. Liang- no conflict of interest Richard B. Buxton- no conflict of interest Scott Letendre- no conflict of interest J. Allen McCutchan – no conflict of interest Ronald J. Ellis- no conflict of interest REFERENCES 1. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146CM156. [PubMed] [Google Scholar] 2. Valcour V, Shikuma C, Shiramizu B, et al. Higher rate of recurrence of dementia in older HIV-1 individuals: the Hawaii Ageing with HIV-1 Cohort. Neurology. 2004;63:822C827. [PMC free article] [PubMed] [Google Scholar] 3. Buxton RB, Uludag K, Dubowitz DJ, Liu TT. Modeling the hemodynamic response to mind activation. Neuroimage. 2004;23 Suppl 1:S220CS233. [PubMed] [Google Scholar] 4. Chang L, Tomasi D, Yakupov R, et al. Adaptation of the Enzastaurin cost attention network in human being immunodeficiency virus mind injury. Ann Neurol. 2004;56:259C272. [PubMed] [Google Scholar] 5. Wong EC, Buxton RB, Frank LR. Quantitative imaging of perfusion using a solitary subtraction (QUIPSS and QUIPSS II) Magnetic Resonance in Medicine. 1998;39:702C708. [PubMed] [Google Scholar] 6. Wang J, Qiu M, Constable RT. In vivo method for correcting transmit/receive nonuniformities with phased array coils. Magn Reson Med. 2005;53:666C674. [PubMed] [Google Scholar] 7. Ances BM, Liang CL, Leontiev O, et al. Effects of ageing on cerebral blood flow, oxygen metabolism, and blood oxygenation level dependent responses to visual stimulation. Hum Mind Mapp. 2008 [PMC free article] [PubMed] [Google Scholar] 8. van Gorp WG, Miller EN, Marcotte TD, et al. The relationship between age and cognitive impairment in HIV-1 illness: findings from the Multicenter AIDS Cohort Study and a medical cohort. Neurology. 1994;44:929C935. [PubMed] [Google Scholar] 9. Chang L, Wong V, Nakama H, et al. Greater than age-related changes in mind diffusion of HIV individuals after 1 year. J Neuroimmune Pharmacol. 2008;3:265C274. [PMC free article] Enzastaurin cost [PubMed] [Google Scholar] 10. Ernst T, Chang L. Effect of ageing on brain metabolism in antiretroviral-naive HIV individuals. Helps. 2004;18 Suppl 1:S61CS67. Mouse monoclonal to PGR [PubMed] [Google Scholar] 11. Thompson PM, Dutton RA, Hayashi KM, et al. Thinning of the cerebral cortex visualized in HIV/Helps displays CD4+ T Enzastaurin cost lymphocyte decline. Proc Natl Acad Sci U S A. 2005;102:15647C15652. [PMC free of charge content] [PubMed] [Google Scholar] 12. Ross MH, Yurgelun-Todd DA, Renshaw PF, et al. Age-related decrease in useful MRI response to photic stimulation. Neurology. 1997;48:173C176. [PubMed] [Google Scholar] 13. Buckner RL, Snyder AZ, Sanders AL, Raichle Myself, Morris JC. Functional human brain imaging of youthful, nondemented, and demented old adults. J Cogn Neurosci. 2000;12 Suppl 2:24C34. [PubMed] [Google Scholar] 14. Ances BM, Roc AC, Wang J, et al. Caudate blood circulation and quantity are low in HIV+ neurocognitively impaired sufferers. Neurology. 2006;66:862C866. [PubMed] [Google Scholar] 15. Haughey NJ, Steiner J, Nath A, et al. Converging functions for sphingolipids and cellular tension in the progression of neuro-AIDS. Entrance Biosci. 2008;13:5120C5130. [PMC free content] [PubMed] [Google Scholar].

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